2009 SantosJavier Santos, M.D.

Hospital General Vall d’Hebron, Barcelona, Spain

Dr. Santos is the 2009 recipient of the IFFGD Research Award Junior Investigator – Clinical Science. Dr. Santos's research focuses on the pathogenesis of irritable bowel syndrome (IBS). He is pursuing, through a comprehensive approach, a detailed knowledge of physiology and sequential pathophysiology of chronic intestinal inflammation, as a potential nexus to prevalent digestive diseases associated with changes in barrier function, motility and visceral sensitivity. In particular, he is studying a prominent feature in the intestine of certain IBS subgroups, the presence of mucosal inflammation and immune activation and its link to IBS symptoms. He is studying the role of psychosocial stress and its ability to disturb the functional homeostasis inherent to the gut epithelial barrier, as well as gender-related susceptibility for IBS.