Norman Barrett was a pathologist. In 1950, he described an abnormality in the lining of the lower esophagus that bears his name (i.e., Barrett’s esophagus). We now believe that it is due to severe, longstanding, gastroesophageal reflux disease (GERD). Significantly, most people with GERD have no such abnormality. Nevertheless, the presence of Barrett’s esophagus is an important observation since those who have it are at greater than normal risk of developing cancer of the esophagus. A review of diagnosis, management, and treatment. Revised and updated 2012.