Acute Hepatic Porphyria (AHP)

Acute hepatic porphyria (AHP) is a group of rare genetic conditions that can cause severe, sudden (acute) symptoms. These symptoms can happen in various parts of the body and often require a hospital visit. There are four types of AHP which include: acute intermittent porphyria, variegate porphyria, hereditary coproporphyria, and ALAD-deficient porphyria. It is estimated […]

Chronic Constipation

Chronic, long-term or recurring, constipation is more challenging to treat than common simple constipation. People who are constipated may experience any one or more of the following: reduced stool frequency, hard stools, difficulty passing stools, straining, painful bowel movements, or feeling of incomplete emptying after defecation. Most of us experience constipation from time to time. […]

Gastroparesis

Gastroparesis (GP) is a condition of slowed stomach emptying with no intestinal blockage. Healthcare providers often refer to this as delayed gastric emptying. This is considered a motility disorder where the stomach does not empty food as quickly as it should. Motility describes the movement of food and fluids through the gastrointestinal (GI) tract. Symptoms […]

Clostridioides Difficile Infection (CDI)

Clostridioides difficile Infection (CDI) or C. difficile is the major cause of infectious colitis and diarrhea in healthcare settings around the world. Infectious colitis is redness, swelling, and inflammation of the colon. (It was formerly known as Clostridium difficile; however, was renamed as after it was reclassified in 2016.) How does Clostridioides Difficile Infections Spread? […]

Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is characterised by chronic irritation and ulcers in the gastrointestinal tract; Crohn’s disease and ulcerative colitis are the most common disorders. The disorders can develop in any age group but are usually diagnosed between the ages of 15 and 30. What is Crohn’s disease? The digestive system Crohn’s disease is an […]

Irritable Bowel Syndrome

IBS affects up to 5-10% of individuals worldwide and affects children and adults of both genders. Although IBS does not shorten a person’s life span, it is associated with a large health care and economic burden. Irritable bowel syndrome (IBS) is a disorder in which people have reoccurring issues with abdominal discomfort or pain that […]

Sphincter of Oddi Dysfunction

The sphincter of Oddi is a muscular valve that controls the flow of digestive juices (bile and pancreatic juice) through ducts from the liver and pancreas into the first part of the small intestine (duodenum). Sphincter of Oddi dysfunction (SOD) describes the situation when the sphincter does not relax at the appropriate time (due to […]

Intestinal Pseudo-obstruction

Intestinal pseudo-obstruction is a rare condition with symptoms like those caused by a bowel obstruction, or blockage. But when the intestines are examined, no blockage is found. Instead, the symptoms are due to nerve (visceral neuropathy) or muscle (visceral myopathy) problems that affect the movement of food, fluid, and air through the intestines. The intestines, […]

Diverticulosis and Diverticulitis

Note: Many disorders can affect the digestive tract. Some can have symptoms that may be similar to or overlap with gastrointestinal (GI) functional or motility disorders. These will have uniquely identifying features which differentiate them from functional GI or motility disorders. What is Diverticulosis and Diverticulitis? Diverticulosis: Diverticulosis is the condition of having small pouches […]

Centrally Mediated Abdominal Pain Syndrome (CAPS)

People with functional gastrointestinal (GI) disorders can have a variety of symptoms that range from painless diarrhea or constipation to pain associated with diarrhea and/or constipation (usually called irritable bowel syndrome). There is another, less common condition of abdominal pain that is chronic or frequently recurring; it is not associated with changes in bowel pattern […]

Volvulus

  Volvulus is a condition in which the bowel twists on itself, causing obstruction to the flow of material through the bowel. It can also lead to obstruction of the blood supply to the intestine itself, which can result in tissue death within the bowel.[1] It is most commonly due to a birth defect called […]

Globus

Globus (Latin for globe or ball) is the sensation of a lump or ball in the throat, typically felt in the throat at the level of the Adam’s apple. It is commonly experienced with an intense emotional experience such as stress. The “globus response” is a common human experience. Globus seems equally prevalent in men […]